Clinical efficacy and safety of a single administration of fluralaner injectable suspension (BRAVECTO^® injectable) vs. monthly administration of oral afoxolaner (NexGard^®) in dogs for tick and flea control over one year under European field conditions.

ABSTRACT:

Background

Year-round control of canine flea and tick infestations requires owner compliance with recommendations for regular treatments. Compliance failures can result in increased exposure of dogs to tick-borne pathogens and resurgence of flea populations. This study investigated the year-long efficacy of fluralaner 150 mg/ml injectable suspension (BRAVECTO^® injectable), developed to remove the need for multiple owner-administered, within-year treatments.

Methods

This randomized, examiner-masked, non-inferiority study enrolled household dogs at veterinary clinics in Germany, France, and Spain. Each household contained a primary dog infested with ≥ 4 ticks or ≥ 5 fleas. Additional dogs in each household received the same treatment as the primary dog, either a sin

SUBMITTER: Petersen I 

PROVIDER: S-EPMC11626764 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature