Association between white matter microstructural changes and aggressiveness. A case-control diffusion tensor imaging study.

ABSTRACT: Research has focused on identifying neurobiological risk factors associated with aggressive behavior in order to improve prevention and treatment efforts. This study aimed to characterize microstructural differences in white matter (WM) integrity in individuals prone to aggression. We hypothesized that altered cerebral WM microstructure may underlie normal individual variability in aggression and tested this using a case-control design in healthy individuals. Diffusion tensor imaging (DTI) was used to examine WM changes in martial artists (n = 29) and age-matched controls (n = 31). We performed tract-based spatial statistics (TBSS) to identify differences in axial diffusivity (AD), fractional anisotropy (FA) and mean diffusivity (MD) between the two groups at the whole-brain level. Martial

SUBMITTER: Seidenbecher S 

PROVIDER: S-EPMC11626826 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature