Preoperative susceptibility to developing secondary hyperalgesia is associated with post-thoracotomy pain at 2 months.

ABSTRACT:

Background

Identifying the subset of patients at risk for developing persistent pain after surgery is clinically important as they could benefit from targeted prevention measures. In this prospective study, we investigated if the preoperative assessment of the individual susceptibility to developing experimentally induced secondary hyperalgesia is associated with post-thoracotomy pain at 2 months.

Methods

Forty-one patients scheduled to undergo a posterolateral thoracotomy were recruited before surgery and followed prospectively for 2 months. The day before surgery, we experimentally induced secondary hyperalgesia at one of the two forearms and measured the change of perception to mechanical pinprick stimuli and the area of hyperalgesia. On postoperative Day 4, Day 15 and at

SUBMITTER: Gousset S 

PROVIDER: S-EPMC11627004 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature