Viral genomic methylation and the interspecies evolutionary relationships of ranavirus.

ABSTRACT: Ranaviruses are capable of infecting both wild and farmed fish, amphibians, and reptiles, leading to significant economic losses and ecological risks. Currently, ranaviruses have been found in at least 175 species spanning six continents. Except for Singapore grouper iridovirus (SGIV), ranavirus genomes are generally regarded as highly methylated. Nevertheless, our comprehension of the methylation characteristics within ranaviruses remains limited. Despite the numerous genomes currently included in the GenBank database, a complete phylogenetic tree for ranaviruses has not yet been determined, and interspecific evolutionary relationships among ranaviruses have not been thoroughly investigated. In this study, the whole-genome methylation profile of mandarin fish ranavirus (MRV; a ranavirus)

SUBMITTER: Pan W 

PROVIDER: S-EPMC11627377 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature