Time as a significant factor in the release of potassium from lithium heparin plasma and serum.

ABSTRACT:

Objectives

In most countries the majority of patients are in outpatient care. In difference to hospitalized patients, their blood samples often take hours after collection to centrifugation. The study investigates the release of potassium and the development of pseudohyperkalemia in lithium heparin (Li-Hep) and serum blood collection tubes over time.

Methods

From 201 donors 4 serum and 4 Li-Hep blood collection tubes were taken each. After 0.5, 4, 6 and 8h whole blood was centrifuged, and potassium levels were determined. To simulate the preanalytic conditions, the samples with a storage time >0.5h were shaken on a standard shaker for 1h and stored at 4-8°C for the remaining time.

Results

Over time, significant more potassium was released before centrifugation from th

SUBMITTER: Reuter T 

PROVIDER: S-EPMC11627413 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature