Genotyping and drug susceptibility profiling of Prototheca sp. strains isolated from cases of protothecosis in dogs.

ABSTRACT:

Background

Protothecosis in dogs is a rare, yet emerging disease, distinguished by its often-aggressive clinical course and high fatality rate. Our study was conducted to enhance treatment protocols for affected dogs by better understanding the genetic diversity and drug resistance patterns of Prototheca species.

Objectives

To identify species and drug susceptibility profiles of an international collection of 28 Prototheca strains isolated from cases of protothecosis in dogs.

Animals

None.

Methods

Retrospective study. Species-level identification was made for isolates from 28 dogs in 6 countries by molecular typing with the partial cytb gene as a marker. For the determination of minimum inhibitory concentrations (MICs) and minimum algicidal concentrations (MACs

SUBMITTER: Proskurnicka A 

PROVIDER: S-EPMC11627519 | biostudies-literature | 2025 Jan-Feb

REPOSITORIES: biostudies-literature