Nucleated red blood cells for characterization of systemic inflammatory response syndrome in dogs.

ABSTRACT:

Background

Nucleated red blood cells (nRBCs) are increased by disease processes and hematopoietic stress.

Objectives

To evaluate the utility of nRBCs as a marker of disease severity and prognosis in dogs with systemic inflammatory response syndrome (SIRS).

Animals

Sixty-two client-owned dogs met the criteria of SIRS without anemia.

Methods

nRBC-positive (nRBCs: ≥5/500, n = 32) and nRBC-negative (nRBCs: <5/500, n = 30) dogs were classified, and clinicopathological data, Acute Patient Physiologic and Laboratory Evaluation (APPLE_fast) scores, cytokines, 2- and 4-weeks survival were compared.

Results

The median WBC (17.63, interquartile range [IQR]: 11.72-20.24 × 10⁹/L), neutrophils (12.28, IQR: 7.17-16.88 × 10⁹/L), band neut

SUBMITTER: Cho A 

PROVIDER: S-EPMC11627520 | biostudies-literature | 2025 Jan-Feb

REPOSITORIES: biostudies-literature