Comparative metagenomics of microbial communities and resistome in southern farming systems: implications for antimicrobial stewardship and public health.

ABSTRACT: Agricultural practices significantly influence microbial diversity and the distribution of virulence and antimicrobial resistance (AMR) genes, with implications for ecosystem health and food safety. This study used metagenomic sequencing to analyze 60 samples (30 per state) including water, soil, and manure (10 each) from Alabama (a mix of cattle and poultry sources) and Tennessee (primarily from cattle). The results highlighted a rich microbial diversity, predominantly comprising Bacteria (67%) and Viruses (33%), with a total of over 1,950 microbial species identified. The dominant bacterial phyla were Proteobacteria, Cyanobacteria, Actinobacteria, Firmicutes, and Bacteroidetes, with the viral communities primarily represented by Phixviricota and Uroviricota. Distinct state-specific micro

SUBMITTER: Kilonzo-Nthenge A 

PROVIDER: S-EPMC11628260 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature