High-Performance Dopamine-Based Supramolecular Bio-Adhesives.

ABSTRACT: The need for wound closure or surgical procedures has been commonly met by the application of sutures. Unfortunately, these are often invasive or subject to contamination. Alternative solutions are offered by surgical adhesives that can be applied and set without major disruption; a new class of supramolecular-based adhesives provides potential solutions to some of these challenges. In this study, a series of polymers utilizing dopamine as a self-assembling unit are synthesized. It is found that these motifs act as extremely effective adhesives, with control over the mechanical strength of the adhesion and materials' tensile properties enabled by changing monomer feed ratios and levels of cross-linking. These materials significantly outperform commercially available bio-adhesives, showing

SUBMITTER: Hagemann MJL 

PROVIDER: S-EPMC11628360 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature