Comparison of different exercise modalities on fatigue and muscular fitness in patients with multiple sclerosis: a systematic review with network, and dose-response meta-analyses.

ABSTRACT:

Background

Fatigue and muscular fitness are closely related to the quality of life in patients with multiple sclerosis (MS). However, the optimal exercise dosage to improve these outcomes remains unclear.

Objective

We evaluated the effects of different exercise modalities and dosages on fatigue levels and muscular fitness in patients with MS.

Methods

A systematic search was conducted across five electronic databases, including randomized controlled trials involving exercise interventions for patients with MS. The data covered literature from the establishment of each database up to August 2024. Two independent reviewers assessed the quality of the studies. Network and dose-response meta-analyses were performed using a random-effects model to evaluate the impact of exe

SUBMITTER: Zhang XN 

PROVIDER: S-EPMC11628374 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature