Liquid Chromatography Column Screening for the Analysis of Corrosion Inhibitor Molecules Using Derringer Desirability Functions.

ABSTRACT: Corrosion inhibitors (CIs) are extensively employed in the oil and gas industry, yet their analysis remains a challenge. To develop a suitable liquid chromatography method for a wide array of CIs, a column screening was conducted. Nine different chromatographic conditions were tested across eight RPLC and mixed-mode columns (Accucore C18, CORTECS Shield RP18, Acquity HSS T3, Acquity Premier HSS T3, Accucore 150-C4, Accucore PFP, Synergi Polar RP, and Acclaim WCX-1). Seven model mixtures representative of CIs, which included quaternary ammoniums, imidazolines, and phosphoric esters, were considered to probe the columns. Each column exhibited unique analytical performances, peak shape, and separation profiles. To find a compromise to analyze all the mixtures with one method, Derringer desira

SUBMITTER: Furno L 

PROVIDER: S-EPMC11628455 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature