The World Trade Center exposome and health effects in 9/11 rescue and recovery workers.

ABSTRACT:

Background

In the aftermath of the World Trade Center (WTC) attack on 11 September 2001, rescue and recovery workers faced hazardous conditions and toxic agents. Prior research linked these exposures to adverse health effects, but mainly examined individual factors, overlooking complex mixture effects.

Methods

This study applies an exposomic approach encompassing the totality of responders' experience, defined as the WTC exposome. We analyzed data from 34,096 members of the WTC Health Program General Responder, including mental and physical health, occupational history, traumatic and environmental exposures using generalized weighted quantile sum regression.

Results

We find a statistically significant association between the exposure mixture index and all investigated

SUBMITTER: Rechtman E 

PROVIDER: S-EPMC11628551 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature