Second phase Chiba study of mother and child health (C-MACH): Japanese birth cohort study with multiomics analyses.

ABSTRACT:

Purpose

Epidemiological studies have reported that environmental factors from fetal period to early childhood can influence the risk of non-communicable diseases in adulthood. This concept has been termed the developmental origins of health and disease (DOHaD). The Chiba study of Mother and Child Health (C-MACH) is a DOHaD concept-based birth cohort study which started in 2014. This study aims to investigate the effects of genetic and environmental factors, particularly fetal and postnatal living environment, on children's health. We also aim to identify candidate biomarkers for their health status. Moreover, the second phase study of C-MACH which was initiated in 2021 aimed at expanding the sample size, especially for gut microbiota and epigenomic analysis; it also aimed at clarif

SUBMITTER: Koshizaka M 

PROVIDER: S-EPMC11628962 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature