Evaluating transportability of overall survival estimates from US to UK populations receiving first-line treatment for advanced non-small cell lung cancer: a retrospective cohort study.

ABSTRACT:

Objectives

The objective of this study is to explore how the UK versus the USA compare in patient characteristics, treatment patterns and overall survival (OS) of patients with advanced non-small cell lung cancer (aNSCLC) initiating first-line (1L) treatment.

Design

Retrospective cohort study.

Setting

Oncology treatment centres in the USA and UK.

Participants

People in the USA and UK diagnosed with aNSCLC and treated in the 1L setting between 2016 and 2018. The US cohort was obtained from a nationwide electronic health record-derived deidentified database. The UK cohort information was derived from a published study exploring the patient characteristics, treatments and outcomes of people with aNSCLC in the UK.

Interventions

1L chemotherapy, immunotherapy

SUBMITTER: Kent S 

PROVIDER: S-EPMC11628978 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature