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Impact of exposure to extreme heat events during pregnancy on the incidence of congenital heart disease in offspring: a meta-analysis.


ABSTRACT:

Background

The aetiology of congenital heart disease (CHD) is multifactorial. Environmental risk factors have emerged as an important modifiable determinant of several congenital cardiac conditions. Previous studies have shown a strong relationship between CHD and air pollution. Much less is known about the influence of ambient temperature on CHD. The primary objective of this meta-analysis was to examine the association between exposure to extreme heat events (EHE) during pregnancy and CHD in the offspring.

Methods

comprehensive literature search was conducted using electronic databases such as Scopus and PubMed, along with a review of secondary references. This process yielded eight studies that met the inclusion criteria: four from the USA, two from China, one from Israel

SUBMITTER: Krishnakumar M 

PROVIDER: S-EPMC11629000 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature