Exploring brain perfusion in dogs with meningoencephalitis of unknown origin: A promising role for arterial spin labeling imaging.

ABSTRACT:

Background

Arterial spin labeling (ASL) is a noninvasive brain perfusion magnetic resonance imaging (MRI) technique that has not been assessed in dogs with meningoencephalitis of unknown origin (MUO).

Hypothesis/objectives

Assess brain perfusion changes characteristics before and after medical treatment, and investigate the role of ASL perfusion in the diagnosis and prognosis of MUO in dogs.

Animals

Thirty-one dogs with presumed MUO.

Methods

Prospective study. Each animal had brain MRI including standard and ASL perfusion sequences at presentation and after treatment of 3 months or longer. Brain perfusion characteristics were assessed visually and by cerebral blood flow (CBF) measurements. Perfusion characteristics were compared pre- and post-treatment.

Resu

SUBMITTER: Arti L 

PROVIDER: S-EPMC11629257 | biostudies-literature | 2025 Jan-Feb

REPOSITORIES: biostudies-literature