Immunogenicities of vaccines including the immunoglobulin M-degrading enzyme of Streptococcus suis, rIde _Ssuis , and protective efficacy against serotype 14 in piglets.

ABSTRACT: Streptococcus suis (S. suis) is a major porcine pathogen. Some strains have a substantial zoonotic potential such as serotype (cps) 14 as the second most important cps in human infections. To this date no licensed S. suis vaccine is available in Europe though subunit vaccines and bacterins have been examined by several scientific groups worldwide. Objectives of this study were to determine protective efficacy of rIde _Ssuis vaccination against intranasal S. suis cps14 challenge in conventional weaned piglets and to investigate additionally immunogenicity of rIde _Ssuis vaccination in cesarean-derived colostrum-deprived (CDCD) piglets. Immunization led to reduction of bacterial multiplicity in porcine blood and dela

SUBMITTER: Mayer L 

PROVIDER: S-EPMC11629322 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature