On-treatment clinical remission of severe asthma with real-world longer-term biologic use.

ABSTRACT:

Background

There are limited real-world data describing the proportion of patients with severe asthma (SA) who achieve on-treatment clinical remission with long-term biologic treatment.

Objective

Our aim was to examine the proportion and characteristics of adults with SA who achieved clinical remission with biologic therapy.

Methods

CHRONICLE is an observational study of US subspecialist-treated adults with SA. Sites reported exacerbations and biologic use from 12 months before enrollment forward. Monthly Asthma Control Test scores and 6-monthly specialist assessments of asthma control were collected. Patients who enrolled from February 2018 to February 2023, began taking a biologic during the study observation period, and continued use of that biologic for at least 1

SUBMITTER: Chipps BE 

PROVIDER: S-EPMC11629328 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature