Low cost, portable, 3D printable tissue precision slicer.

ABSTRACT: Slicing tissue samples into thin pieces is commonly used in histology analysis and more recently for organotypic culture when tissue samples are sliced alive. Currently available devices for slicing tissue samples are either designed for fixed tissue samples at low cryogenic temperatures (e.g., Cryostats), or bulky and expensive (e.g., vibratome), preventing them from routine lab usage. Here we report a cost-effective device designed to section live tissues for subsequent culture. This device consists of components crafted from 3D-printed Nylon-12- a material suitable for autoclaving to ensure sterility. Its small footprint enhances portability, allowing for convenient placement within a biosafety cabinet for an added layer of sterility assurance. Using human pluripotent stem

SUBMITTER: Martinez-Martin B 

PROVIDER: S-EPMC11629332 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature