Additive outcome of platelet rich fibrin neourethral coverage of tubularized incised plate in primary distal hypospadias repair.

ABSTRACT:

Background

Healing complications are a significant concern after hypospadias repair, often attributed to deficient growth factors and reduced healing potential of hypospadiac tissue. Platelet-Rich Fibrin (PRF), a new generation of platelet concentrates rich in growth factors, has been successfully applied to provide a mechanical barrier and promote healing in different surgical fields. The objective of this study was to assess the role of a PRF membrane covering the neourethra, in addition to a Dartos flap, optimizing the outcomes of primary distal hypospadias repair.

Methods

Forty-four patients undergoing primary distal hypospadias repair were randomized and then assigned to two groups according to the covering layer(s) applied over the neourethra in Tubularized Incised Pla

SUBMITTER: Mansour AM 

PROVIDER: S-EPMC11629491 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature