Successful diagnosis and treatment of canine polymyositis: utilizing MRI and immunohistochemistry for accurate detection.

ABSTRACT:

Background

Inflammatory myopathy is generally categorized into generalized inflammatory myopathies (gIM), which affect muscles throughout the body, and focal inflammatory myopathies (fIM), which are localized to specific muscles or muscle groups. This report details a case of immune-mediated polymyositis in a dog, successfully diagnosed using MRI and IHC and managed with immunosuppressive therapy.

Case presentation

A 5-year-old castrated male Poodle was admitted to our hospital presenting with lethargy and exercise intolerance. Biochemical analysis revealed significantly elevated serum levels of aspartate aminotransferase (AST) and creatine kinase (CK). Physical examination showed muscle atrophy in the hind legs, but further orthopedic and neurological examinations identifie

SUBMITTER: Han J 

PROVIDER: S-EPMC11629501 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature