Brain and brain blood vessels histological description in autopsies of fetuses/neonates born to mothers with hypertension during pregnancy. A case-control study.

ABSTRACT:

Background

Children born to women with hypertension during pregnancy have a two to threefold increased risk of developing cognitive disorders compared to children born to women without hypertension. However, structural changes in the central nervous system of these children remain poorly understood. We aim to compare the brain histological findings from autopsies of neonates and fetuses born to women with and without hypertension during pregnancy.

Methods

This retrospective case-control study includes brain histological samples from autopsies of neonates and fetuses born to women with (n = 22) and without (n = 15) hypertension during pregnancy, obtained from biobanks associated with the University Hospital San Ignacio (HUSI), Bogotá, Colombia, between 2007 and 2022. Hyperten

SUBMITTER: Gonzalez J 

PROVIDER: S-EPMC11629548 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature