MRNA COVID-19 vaccine safety among children and adolescents: a Canadian National Vaccine Safety Network cohort study.

ABSTRACT:

Background

The Canadian National Vaccine Safety Network conducted active safety surveillance for COVID-19 vaccines. This study aimed to characterize the short-to-medium term safety of mRNA COVID-19 vaccines across the pediatric age spectrum.

Methods

In this cohort study, vaccinated and unvaccinated children and adolescents aged 6 months to 19 years from eight Canadian provinces and territories were invited to participate. The outcome was a health event preventing daily activities, resulting in school absenteeism, or requiring medical consultation. Age-stratified multivariable regression models were used to examine health events associated with first and second doses of mRNA COVID-19 vaccines across different age groups: children under 5, children aged 5-11 years and adolesce

SUBMITTER: Soe P 

PROVIDER: S-EPMC11629564 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature