Implementing Oral Antibiotics for Bone and Joint Infections: Lessons Learned and Opportunities for Improvement.

ABSTRACT:

Background

Although intravenous antibiotics have historically been the standard of care for bone and joint infections, clinical trial data have highlighted the safety and efficacy of oral antibiotics. Despite this, intravenous antibiotics are still commonly used, and evaluations of institutional guidelines advancing oral antibiotic use are limited.

Methods

In April 2023, we implemented a new institutional guideline to preferentially treat patients with bone and joint infections with oral antibiotics. The postguideline cohort was compared with a historical preguideline cohort via retrospective chart review. The primary outcome was the proportion of patients discharged exclusively on oral antibiotics. Secondary outcomes included 90-day treatment failure, length of stay, and ad

SUBMITTER: Hawkins MR 

PROVIDER: S-EPMC11629981 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature