FEHAT: efficient, large scale and automated heartbeat detection in Medaka fish embryos.

ABSTRACT:

Summary

High-resolution imaging of model organisms allows the quantification of important physiological measurements. In the case of fish with transparent embryos, these videos can visualize key physiological processes, such as heartbeat. High throughput systems can provide enough measurements for the robust investigation of developmental processes as well as the impact of system perturbations on physiological state. However, few analytical schemes have been designed to handle thousands of high-resolution videos without the need for some level of human intervention. We developed a software package, named FEHAT, to provide a fully automated solution for the analytics of large numbers of heart rate imaging datasets obtained from developing Medaka fish embryos in 96-well plate format

SUBMITTER: Ferreira MS 

PROVIDER: S-EPMC11630063 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature