Development of slow oscillation-spindle coupling from infancy to toddlerhood.

ABSTRACT: Sleep has been demonstrated to support memory formation from early life on. The precise temporal coupling of slow oscillations (SOs) with spindles has been suggested as a mechanism facilitating this consolidation process in thalamocortical networks. Here, we investigated the development of sleep spindles and SOs and their coordinate interplay by comparing frontal, central, and parietal electroencephalogram recordings during a nap between infants aged 2-3 months (n = 31) and toddlers aged 14-17 months (n = 49). Spindles and SOs showed quite different maturational patterns between age groups, as to topography, amplitude, and density. Notably, spindle-SO co-occurrence in the infants did not exceed chance levels and was increased to significant levels only in the toddlers. In the

SUBMITTER: Kurz EM 

PROVIDER: S-EPMC11630081 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature