Does Improving Depression Symptoms in Young Adults With Inflammatory Bowel Disease Alter Their Microbiome?

ABSTRACT:

Background

Patients with inflammatory bowel diseases (IBDs) are more likely to have depression and anxiety symptoms compared with healthy individuals and those with other chronic illnesses. Previous studies have shown a link between the microbiome composition and depression symptoms; however, many antidepressant medications have antibacterial activity confounding cross-sectional studies of these populations. Therefore, we aimed to determine whether we could detect longitudinal changes in the microbiome of a subset of patients who participated in a previously published mindfulness-based cognitive therapy (MBCT) study to improve depression symptoms in adolescents and young adults with IBD.

Methods

Stool samples were collected at baseline and 8 weeks (n = 24 participants, 37 to

SUBMITTER: Davies JM 

PROVIDER: S-EPMC11630472 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature