BMScope: A scoping review to chart the evolving clinical study landscape in brain and leptomeningeal metastasis.

ABSTRACT:

Background

Recent studies have challenged the notion that patients with brain metastasis (BM) or leptomeningeal metastasis (LM) should be excluded from systemic therapy clinical trials. This scoping study summarizes the BM/LM clinical studies published between 2010 and 2023.

Methods

MEDLINE, CINAHL, CAB Abstracts, PsycINFO, Cochrane Library, HINARI, International Pharmaceutical Abstracts, PubMed, Scopus, Web of Science, and EMBASE electronic databases were searched on June 21, 2021. An updated search was performed on February 21, 2023. Eligible studies investigated a therapeutic intervention in solid tumor patients with BM and/or LM and reported a patient outcome. Extracted study-level data, including study type, publication date, geographical location, number of BM/LM patie

SUBMITTER: Cheng VWT 

PROVIDER: S-EPMC11630544 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature