Systematic review of exercise for the treatment of pediatric metabolic dysfunction-associated steatotic liver disease.

ABSTRACT:

Background & aims

Steatotic liver disease affects approximately 1 in 10 children in the U.S. and increases the risk of cirrhosis, diabetes, and cardiovascular disease. Lifestyle modification centered on increased physical activity and dietary improvement is the primary management approach. However, significant gaps in the literature hinder the establishment of exercise as a targeted therapeutic strategy for pediatric metabolic dysfunction-associated steatotic liver disease (MASLD), previously known as nonalcoholic fatty liver disease (NAFLD). We performed a systematic review of studies assessing the impact of exercise interventions on validated hepatic outcomes in children with NAFLD.

Methods

We searched CENTRAL, PubMed, Embase, Web of Science, CINAHL, and Google Scholar on

SUBMITTER: Smith MR 

PROVIDER: S-EPMC11630624 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature