Diagnostic validity and solute-corrected prevalence for hyponatremia and hypernatremia among 1 813 356 admissions.

ABSTRACT:

Background and hypothesis

We aimed to evaluate the diagnostic validity of the International Classification of Diseases, 10th Revision (ICD-10) codes for hyponatremia and hypernatremia, using a database containing laboratory data. We also aimed to clarify whether corrections for blood glucose, triglyceride, and total protein may affect the prevalence and the diagnostic validity.

Methods

We retrospectively identified admissions with laboratory values using a Japanese hospital-based database. We calculated the sensitivity, specificity, and positive/negative predictive values of recorded ICD-10-based diagnoses of hyponatremia (E87.1) and hypernatremia (E87.2), using serum sodium measurements during hospitalization (<135 and >145 mmol/l, respectively) as the reference standard. W

SUBMITTER: Okada A 

PROVIDER: S-EPMC11630772 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature