Disagreement on foundational principles of biological aging.

ABSTRACT: To gain insight into how researchers of aging perceive the process they study, we conducted a survey among experts in the field. While highlighting some common features of aging, the survey exposed broad disagreement on the foundational issues. What is aging? What causes it? When does it begin? What constitutes rejuvenation? Not only was there no consensus on these and other core questions, but none of the questions received a majority opinion-even regarding the need for consensus itself. Despite many researchers believing they understand aging, their understanding diverges considerably. Importantly, as different processes are labeled as "aging" by researchers, different experimental approaches are prioritized. The survey shed light on the need to better define which aging processes this f

SUBMITTER: Gladyshev VN 

PROVIDER: S-EPMC11630784 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature