Rates and predictors of cardiovascular and non-cardiovascular outcomes in heart failure with preserved ejection fraction.

ABSTRACT:

Aims

The detailed sub-categories of death and hospitalization, and the impact of comorbidities on cause-specific outcomes, remain poorly understood in heart failure (HF) with preserved ejection fraction (HFpEF). We sought to evaluate rates and predictors of cardiovascular (CV) and non-CV outcomes in HFpEF.

Methods

The Karolinska-Rennes study was a bi-national prospective observational study designed to characterize HFpEF (ejection fraction ≥45%). Patients were followed for cause-specific death and hospitalization. Baseline characteristics were pre-selected based on clinical relevance and potential eligibility criteria for HFpEF trials. The associations between characteristics and cause-specific outcomes were assessed with univariable and multivariable Cox regressions.

Res

SUBMITTER: Shahim A 

PROVIDER: S-EPMC11631285 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature