Emergent role of dynamic optimization in cardiac resynchronization therapy: Systematic review and network meta-analysis.

ABSTRACT:

Aims

Suboptimal device programming is frequent in non-responders to cardiac resynchronization therapy (CRT). However, the role of device optimization and the most appropriate technique are still unknown. The aim of our study was to analyse the effect of different CRT optimization techniques within a network meta-analysis.

Methods

A systematic search was conducted on MEDLINE, Embase and CENTRAL for studies comparing outcomes with empirical device settings or optimization using echocardiography, static algorithms or dynamic algorithms. Studies investigating the effect of optimization in non-responders were also analysed.

Results

A total of 17 studies with 4346 patients were included in the quantitative analysis. Of the treatments and outcomes examined, a significant dif

SUBMITTER: Zsigmond EJ 

PROVIDER: S-EPMC11631291 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature