Reductions in renin-angiotensin system inhibitors following hospitalization for heart failure.

ABSTRACT:

Aims

Limited data are available that evaluate the efficacy of renin-angiotensin system inhibitor (RASI) dose-reduction in older adults with heart failure with reduced ejection fraction following a heart failure hospitalization.

Methods and results

We examined a 5% random sample of Medicare beneficiaries with prescription coverage who were discharged to home following a hospitalization for heart failure with reduced ejection fraction between 1 January 2007 and 30 June 2018 and were treated with RASI prior to hospitalization. We classified patients into three mutually exclusive groups based on RASI dosage before (prescription fills up to 90 days prior to) and after a hospitalization (prescription fills up to 365 days that were most proximate to the discharge date as possible)-

SUBMITTER: Goyal P 

PROVIDER: S-EPMC11631335 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature