Comparative efficacy of non-pharmacological interventions on xerostomia and salivary flow rate among haemodialysis patients: A systematic review and network meta-analysis.

ABSTRACT:

Background

Xerostomia is a distressing symptom experienced by patients undergoing dialysis. We sought to compare and rank the efficacy of different non-pharmacological interventions on xerostomia and salivary flow rate among dialysis patients.

Methods

A systematic search was conducted in six English-language databases: PubMed, CINAHL, Scopus, Web of Science, Embase and Cochrane Central Register of Controlled Trials, in April 2023. Screening, quality appraisal and data extraction were undertaken by two independent reviewers. A network meta-analysis was performed to assess the relative efficacy of different non-pharmacological interventions.

Results

The analysis included 11 randomized controlled trials involving 739 patients and eight non-pharmacological interventions.

SUBMITTER: Sharifnia AM 

PROVIDER: S-EPMC11631358 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature