Associations between prenatal exposure to environmental phenols and child neurodevelopment at two years of age in a South African birth cohort.

ABSTRACT:

Objective

Evidence suggests that prenatal environmental phenol exposures negatively impact child neurodevelopment, however there is little research on the effects of mixtures of multiple phenol exposures. We analyzed associations between prenatal exposure to phenol mixtures and cognitive neurodevelopment at two years of age among 545 mother-child pairs from the South African Drakenstein Child Health Study.

Material and methods

We measured maternal urine environmental phenol concentrations once during the second trimester of pregnancy. We used the Bayley Scales of Infant and Toddler Development III to assess cognitive development at two years of age. We used linear regression models adjusted for maternal HIV status, maternal age, ethnicity, prenatal tobacco exposure, child se

SUBMITTER: Zhou T 

PROVIDER: S-EPMC11631636 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature