Breast density effect on the sensitivity of digital screening mammography in a UK cohort.

ABSTRACT:

Objectives

To assess the performance of breast cancer screening by category of breast density and age in a UK screening cohort.

Methods

Raw full-field digital mammography data from a single site in the UK, forming a consecutive 3-year cohort of women aged 50 to 70 years from 2016 to 2018, were obtained retrospectively. Breast density was assessed using Volpara software. Examinations were grouped by density category and age group (50-60 and 61-70 years) to analyse screening performance. Statistical analysis was performed to determine the association between density categories and age groups. Volumetric breast density was assessed as a binary classifier of interval cancers (ICs) to find an optimal density threshold.

Results

Forty-nine thousand nine-hundred forty-eight s

SUBMITTER: Payne NR 

PROVIDER: S-EPMC11631811 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature