Ultrahigh-resolution 7-Tesla anatomic magnetic resonance imaging and diffusion tensor imaging of <i>ex vivo</i> formalin-fixed human brainstem-cerebellum complex.

ABSTRACT:

Introduction

Brain cross-sectional images, tractography, and segmentation are valuable resources for neuroanatomical education and research but are also crucial for neurosurgical planning that may improve outcomes in cerebellar and brainstem interventions. Although ultrahigh-resolution 7-Tesla (7T) magnetic resonance imaging (MRI) and diffusion tensor imaging (DTI) reveal such structural brain details in living or fresh unpreserved brain tissue, imaging standard formalin-preserved cadaveric brain specimens often used for neurosurgical anatomic studies has proven difficult. This study sought to develop a practical protocol to provide anatomic information and tractography results of an ex vivo human brainstem-cerebellum specimen.

Materials and methods

A protocol was dev

SUBMITTER: Hanalioglu S 

PROVIDER: S-EPMC11631901 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature