<i>Lactiplantibacillus plantarum</i> L47 and inulin affect colon and liver inflammation in piglets challenged by enterotoxigenic <i>Escherichia coli</i> through regulating gut microbiota.

ABSTRACT:

Introduction

Infection by pathogenic bacteria during weaning is a common cause of diarrhea and intestinal inflammation in piglets. Supplementing the diet with synbiotics is beneficial for animal health. The strain of Lactiplantibacillus plantarum L47 (L47) isolated in our lab exhibited good probiotic properties when combined with inulin. Here, the effectiveness of combining L47 and inulin (CLN) in protecting against enterotoxigenic Escherichia coli (ETEC) induced colon and liver inflammation in weaned piglets was evaluated.

Methods

Twenty-eight piglets aged 21 days were randomly assigned into 4 groups: CON (control), LI47 (oral CLN culture fluid, 10¹⁰ CFU/d of L47 and 1 g/d of inulin), ECON (oral ETEC culture fluid, 10¹⁰ CFU/d), and ELI47

SUBMITTER: Miao J 

PROVIDER: S-EPMC11631943 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature