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Exploring the therapeutic potency of cryptotanshinone in cervical cancer: a multi-omics and network pharmacology approach.


ABSTRACT:

Introduction

Cervical cancer remains a significant challenge in oncology with an escalating demand for novel therapeutic strategies that can navigate the complexities of its pathophysiology. This study elucidated the antineoplastic effects of cryptotanshinone, a derivative of danshen (Salvia miltiorrhiza), a herb widely utilized in traditional Chinese medicine practices.

Methods

Employing a comprehensive multi-omics approach, including transcriptomic, proteomic, and bioinformatics analyses, we investigated the potential effects of cryptotanshinone on cervical cancer through data mining and computational analysis.

Results and discussion

Our results demonstrated that the potential of cryptotanshinone to disrupted cancer cell proliferation and induced apoptosis ma

SUBMITTER: Lu Z 

PROVIDER: S-EPMC11632102 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature