Sleep state-dependent development of resting-state functional connectivity during the preterm period.

ABSTRACT:

Study objectives

The brains of preterm infants exhibit altered functional connectivity (FC) networks, but the potential variation in sleep states and the impact of breathing patterns on FC networks are unclear. This study explores the evolution of resting-state FC from preterm to term, focusing on breathing patterns and distinguishing between active sleep (AS) and quiet sleep (QS).

Methods

We recruited 63 preterm infants and 44 healthy-term infants and performed simultaneous electroencephalography and functional near-infrared spectroscopy. FC was calculated using oxy- and deoxyhemoglobin signals across eight channels. First, FC was compared between periodic breathing (PB) and non-PB segments. Then sleep state-dependent FC development was explored. FC was compared between AS

SUBMITTER: Shiraki A 

PROVIDER: S-EPMC11632190 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature