The Effects of APOE Alleles, Cognitive Activities, and Social Activities on Cognitive Decline in African Americans.

ABSTRACT:

Objectives

Older African Americans are among the fastest-growing populations, yet are underrepresented in studies examining risk factors related to decline. The present study examines whether biological factors (apolipoprotein [APOE] alleles) interact with behavioral factors including cognitive activities (e.g., reading, playing games) and social activities (e.g., participating in social groups) to predict cognitive decline in African Americans.

Methods

In total, 734 African American adults from the Minority Aging Research Study, aged 65 and older (with no known dementia at the time of enrollment), underwent annual cognitive testing for up to 10 years. At baseline, APOE status was determined and participants reported their frequency of participation in social and cognitive a

SUBMITTER: Nsor NA 

PROVIDER: S-EPMC11632228 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature