Bis-Squaramide-Based [2]Rotaxane Hosts for Anion Recognition.

ABSTRACT: The first examples of bis-squaramide axle containing [2]rotaxanes linked via rigid aryl and flexible alkyl spacers synthesised using copper(I) catalysed active metal template methodology are reported. The halide and oxoanion binding properties of the [2]rotaxanes in aqueous-organic solvent media are examined through extensive ¹H-NMR titration experiments to investigate the impact of integrating multiple squaramide motifs on the anion binding capabilities of the interlocked receptors. These studies reveal that the bis-squaramide rotaxane host systems exhibit enhanced halide anion binding capabilities relative to a mono-squaramide axle functionalised rotaxane, demonstrating a rare anti-Hofmeister bias halide anion selectivity trend in aqueous-organic mixtures and highlighting the

SUBMITTER: Arun A 

PROVIDER: S-EPMC11632403 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature