Correlations between 14-gene RNA-level assay and clinical and molecular features in resectable non-squamous non-small cell lung cancer: a cross-sectional study.

ABSTRACT:

Background

Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related death worldwide. Accurate risk stratification is essential for optimizing treatment strategies. A 14-gene RNA-level assay of lung cancer, which involves quantitative reverse transcription polymerase chain reaction (qRT-PCR) analysis of formalin-fixed paraffin-embedded (FFPE) tissue samples, offers a promising approach. The aim of our study was to assess the relationships between risk stratification, as determined by a 14-gene RNA-level assay, and various clinical and molecular characteristics.

Methods

We retrospectively collected the preoperative clinical information and molecular testing information from 102 resectable non-squamous NSCLC patients. The 14-gene RNA-level assay was performed b

SUBMITTER: Huang Z 

PROVIDER: S-EPMC11632416 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature