Influence of pleural invasion on survival in pathologic T3-4N0M0 non-small cell lung cancer: a propensity score matching study based on the Surveillance, Epidemiology, and End Results database.

ABSTRACT:

Background

Pleural invasion (PI) is considered to be an adverse prognostic factor in non-small cell lung cancer (NSCLC). However, the prognostic roles of PI in pathologic (p)T3-4N0M0 NSCLC remain controversial. Therefore, this study aimed to evaluate the predictive value of PI in patients with pT3-4N0M0 NSCLC.

Methods

This study selected 9,185 patients with resected pT3-4N0M0 NSCLC from 2010 to 2019 from the Surveillance, Epidemiology, and End Results (SEER) database. PL0 was defined as lack of PI; PL1 and PL2 as invasion of the elastic layer and of the surface of the visceral pleural invasion (VPI), respectively; and PL3 as the parietal pleura invasion (PPI). Patients were divided into six groups according to PI status and T categories. This study used propensity score matc

SUBMITTER: Zhang W 

PROVIDER: S-EPMC11632439 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature