Associations of the Charlson comorbidity index with depression and mortality among the U.S. adults.

ABSTRACT:

Background

Chronic comorbidities are often associated with higher risks of depression and mortality. This study aims to explore the relationships between the Charlson Comorbidity Index (CCI) and depression, and their combined effect on mortality.

Methods

This study made use of data gathered in the National Health and Nutrition Examination Survey (NHANES) from 2007 to 2018, including a collective of 23,927 adult participants. According to CCI score distribution, CCI was categorized into three groups (T1 with CCI = 0; T2 with CCI = 1; T3 with CCI ≥ 2). In the CCI ≥ 2 group, patients may have two or more chronic diseases. Multivariable logistic regression models were employed to explore the relationship between CCI and depression. The study utilized the Cox proportional hazards

SUBMITTER: Wang YZ 

PROVIDER: S-EPMC11632622 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature