Exposure to air pollution is associated with adipokines in midlife women: The Study of Women's Health Across the Nation.

ABSTRACT: This study examined the associations between ambient air pollution exposure, including fine particulate matter (PM_2.5), nitrogen dioxide (NO₂), and ozone (O₃), with serum levels of high molecular weight (HMW) adiponectin, leptin, and soluble leptin receptors (sOB-R) in midlife women. The analysis included 1551 participants from the Study of Women's Health Across the Nation (median age = 52.3 years) with adipokine data from 2002 to 2003. Annual air pollution exposures were assigned by linking residential addresses with high-resolution machine learning models at a 1-km² resolution. Multivariable linear regression and Bayesian kernel machine regression (BKMR) were used to evaluate the associations for individual pollutants and pollutant mixtures. Af

SUBMITTER: Wang X 

PROVIDER: S-EPMC11632973 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature