SydR, a redox-sensing MarR-type regulator of <i>Sinorhizobium meliloti</i>, is crucial for symbiotic infection of <i>Medicago truncatula</i> roots.

ABSTRACT: Rhizobia associate with legumes and induce the formation of nitrogen-fixing nodules. The regulation of bacterial redox state plays a major role in symbiosis, and reactive oxygen species produced by the plant are known to activate signaling pathways. However, only a few redox-sensing transcriptional regulators (TRs) have been characterized in the microsymbiont. Here, we describe SydR, a novel redox-sensing TR of Sinorhizobium meliloti that is essential for the establishment of symbiosis with Medicago truncatula. SydR, a MarR-type TR, represses the expression of the adjacent gene SMa2023 in growing cultures, and this repression is alleviated by NaOCl, tert-butyl hydroperoxide, or H₂O₂ treatment. Transcriptional psydR-gfp and pSMa2023-<

SUBMITTER: Nazaret F 

PROVIDER: S-EPMC11633110 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature