Identification of <i>Veillonella parvula</i> and <i>Streptococcus gordonii</i> adhesins mediating co-aggregation and its impact on physiology and mixed biofilm structure.

ABSTRACT: The dental plaque is a polymicrobial community where biofilm formation and co-aggregation, the ability to bind to other bacteria, play a major role in the construction of an organized consortium. One of its prominent members is the anaerobic diderm Veillonella parvula, considered a bridging species, which growth depends on lactate produced by oral streptococci. Understanding how V. parvula co-aggregates and the impact of aggregation has long been hampered due to the lack of appropriate genetic tools. Here we studied co-aggregation of the naturally competent strain V. parvula SKV38 with various oral bacteria and its effect on cell physiology. We show that V. parvula requires different trimeric autotransporters of the type V secretion system to adhere to oral stre

SUBMITTER: Dorison L 

PROVIDER: S-EPMC11633186 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature