Seizure prophylaxis in pneumococcal meningitis, cohort study.

ABSTRACT:

Objective

Our aim was to assess seizure development as a complication of pneumococcal meningitis and its possible prevention with antiseizure medication prophylaxis.

Methods

Antiseizure medication (ASM) prophylaxis has been practiced for a long time at our center. We assessed all cases of community-acquired pneumococcal meningitis admitted from January 2010 to April 2021 recorded in our prospective database and conducted further retrospective studies.

Results

Of the 86 cases recorded, 21 (24.4%) developed acute symptomatic seizures, more than half of which (11/21; 52.4%) before admission. Seizure development increased the need for orotracheal intubation and intensive care unit admission, while also lengthening hospital stays and suggesting more risk of death and disab

SUBMITTER: Guillem L 

PROVIDER: S-EPMC11633693 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature